Fight hormone side effects

1, period of use of large doses of corticosteroids, can cause water, salt, sugar, protein and fat metabolism disorder: the performance of the heart-shaped obesity, moon face, hirsutism, weakness, hypokalemia, edema, hypertension, diabetes, clinically known as Cushing's syndrome. These symptoms can be no special treatment, usually on their own after withdrawal subsides, a few months or longer after return to normal. If necessary, can be equipped with antihypertensive, hypoglycemic drugs, and to give low-voltage, low-sugar, high protein diet and potassium and other symptomatic treatment. Therefore, high blood pressure, arteriosclerosis, renal insufficiency and diabetes, should be adequate vitamin D and calcium, corticosteroids should be carefully applied.
2, induced or exacerbated by infections: role of anti-inflammatory corticosteroids, but does not have antibacterial activity, and can reduce the body's resistance to infection, decrease the body's resistance to disease, is conducive to bacterial growth, reproduction and spread. Therefore, the long-term use of corticosteroids may induce infection or make the body to expand or spread of potential foci, but also the rest of the original spread of tuberculosis lesions. In the course of treatment should pay attention to changes in the disease and whether there is cause infection, while giving the anti-infective treatment. drugs,drugs question and answers
3, induce or aggravate peptic ulcer disease: corticosteroids in addition to hinder tissue repair, delayed tissue healing, but also to an increase in gastric acid and pepsin secretion, and reducing the gastric mucus secretion, reduced gastric mucosal resistance, may induce or aggravate stomach and duodenal ulcer bleeding, or even cause gastrointestinal perforation.
4, neurological symptoms: can occur excitement, insomnia, individual patients can induce psychosis, epilepsy can be induced seizures. Therefore, patients tend to have mental illness, mental patients and epilepsy should be banned.
5, adrenal cortical atrophy or dysfunction: a more long-term use of such drugs, because long-term in vivo glucocorticoid levels higher than normal, can cause negative feedback, while under the influence of the hypothalamus and anterior pituitary adrenocorticotropic hormone, the secretion of endogenous glucocorticoids to reduce or lead to adrenal cortex hormone insufficiency. When faced with stress, such as bleeding, infection, can be dizziness, nausea, vomiting, low blood pressure, low blood sugar or hypoglycemia coma. drugs,drugs question and answers

6, the phenomenon of rebound and withdrawal symptoms: long-term use of hormone drugs, symptoms under control, if the reduction is too large or sudden withdrawal, the original symptoms may soon or increase, this phenomenon is called rebound phenomenon. This is because the role of patients' dependence on the hormone or due to symptoms not completely controlled. Treatment measures for the restoration of hormone dosage until symptom control and then slowly reducing.
If the hormone at the same time, in line with the antagonistic hormonal effects of Chinese medicine, these side effects can be mitigated, or even bring an end to the invisible. drugs,drugs question and answers

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large quantities of glucocorticoids can cause a range of adverse reactions, sugar corticosteroid side effects include the following:
glucocorticoid side effects: water and salt metabolism and metabolic disorders
large quantities of glucocorticoids can cause material water and salt metabolism and metabolic disorders, adrenal hyperfunction syndrome category, such as edema, hypokalemia, hypertension, diabetes, skin thinning, moon face, buffalo hump, central obesity, hirsutism, acne, muscle weakness and muscle atrophy and other symptoms generally do not need special treatment, the withdrawal can be self-limiting. But weakness slow and incomplete recovery. Low-salt, low sugar, high protein diet and the addition of potassium chloride and other measures to reduce these symptoms. In addition, glucocorticoids due to inhibition of protein synthesis, trauma patients can delay wound healing. In children may be due to inhibition of the secretion of growth hormone caused a negative nitrogen balance, so that growth is affected.

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glucocorticoid side effects of the two: induced or exacerbated by infection
glucocorticoids inhibit the body's immune function, and no anti-bacterial effect, it is often long-term use can induce infections or increase the infection, the body can still potential foci spread or resurgence of infection focus, in particular, the original resistance to decrease, such as nephrotic syndrome, tuberculosis, aplastic anemia patients. As the use of corticosteroids when patients often feel good about themselves, to cover up the symptoms of infection develop, so the decision to treat should be preceded by the use of long-range physical examination, exclusion of potential infection, the application process also should be alert, when necessary, and effective antimicrobial agents to be combined, with special attention to the potential prevention and treatment of tuberculosis.

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