Arthritis drug

First, non-drug treatment of non-drug treatment

many things, including the patient's health education, self-training, weight loss, aerobic exercise, range of motion training, strength training, the use of tools to help the line, knee varus wedge insoles, occupational therapy and joint protection, life support facilities and so on. United States and Europe over a considerable portion of patients through treatment can reduce symptoms, restore normal life and work. Investment in this area and the concept of health care workers is still relatively weak, and future efforts to strengthen the work of the medical staff at all levels should pay attention.

often appear in patients with knee osteoarthritis, quadriceps muscle weakness, in the past that this is due to disuse atrophy, but recent studies suggest that foreign countries, quadriceps atrophy is not entirely caused by osteoarthritis, and quadriceps muscle weakness may be the cause of knee osteoarthritis risk factor, due to the weakening of the quadriceps muscle strength, knee stability is affected, normal muscles The buffering capacity should be reduced, thus strengthening the quadriceps muscle strength training and aerobic training on bone arthritis patients is beneficial.

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cure for treatment of osteoarthritis have it?

(1) hyaluronic acid (Al-governance, Haier root Sofastin): The main component of intra-articular synovial fluid, as a component of cartilage matrix, the grease in the joints to reduce the friction between organizations, intra-articular injection can significantly improve the synovial tissue after the inflammation, and enhance the viscosity of synovial fluid and lubricating, protecting the articular cartilage, promote healing and regeneration of articular cartilage, relieve pain, increase joint the activity. Often in the intra-articular injection, 1 25mg, 1 week 1 time for 5 weeks, to strictly aseptic technique.
(2) Glucosamine (Portugal force): to constitute the matrix of articular cartilage together glucosamine (GS) and proteoglycan of the most important simple sugars, normal glucose can be synthesized amino GS, but osteoarthritis, the cartilage cells are blocked or inadequate synthesis of GS, leading to softening of the cartilage matrix and loss of elasticity, collagen fiber structural damage, increase in the bone lacunar cartilage wear and damage. Glucosamine can block the pathogenesis of osteoarthritis, the cartilage cells to promote synthesis of proteoglycan with normal structure, and inhibit the damaged tissue and cartilage of the enzyme (eg collagenase, phospholipase A2) production and reduce damage to the cartilage cells to improve joint motion, relieve joint pain, slow disease course of osteoarthritis. Oral 1 250 ~ 500mg, 1 3 times a day, taking the best dining. drugs,drugs question and answers
(3) non-steroidal analgesic anti-inflammatory drugs: inhibit cyclooxygenase and prostaglandin synthesis, fight inflammation, relieve joint swelling and pain. Choice of ibuprofen 1 200 ~ 400mg, 1 3 times a day; or zinc Glucosamine U.S. 1 200mg, 1 3 times a day; nimesulide (Yi Mei Li) 1 100mg, 1 to 2 times for 4 ~ 6 weeks.

Source: China Pharmaceutical Association website experts
three intra-articular injection

This is also a way to relieve joint symptoms, treatments, drugs commonly used transparent quality acid preparations and glucocorticoids, the former in the country has been in clinical use for some time, have a certain effect. Mechanism is mainly inhibition of inflammatory mediators, such as cell KT and prostaglandin; stimulate cartilage matrix synthesis and inhibit cartilage degradation; analgesic effect but a slower. The analgesic effect of glucocorticoids appears fast. It should be noted that intra-articular injection therapy is a invasive operation, to avoid iatrogenic joint infection, the application of corticosteroids to be careful.

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IV

surgical treatment of osteoarthritis symptoms of very serious medical treatment fails, and the impact of the patient's daily life, we should consider surgical intervention. Osteoarthritis of the knee, it was argued first arthroscopic dissection, this type of surgery for some patients after a certain effect recently, but long-term effect can not be sure. Joint replacement surgery for the majority of osteoarthritis, osteonecrosis, rheumatoid arthritis patients, relieve pain, restore joint function has a significant effect, but there are some joint replacement surgery as the immediate and long-term complications, such as parts The loosening and wear, osteolysis, these complications is still not fully resolved. Therefore, strict control of joint replacement surgery is very important indications. Strictly speaking, the indications for surgery include:

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